Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14

Amyloid and amyloid-like protein aggregations are hallmarks of multiple, varied neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. We previously reported that spinocerebellar ataxia type 14 (SCA14), a dominant-inherited neurodegenerative disease that affects cereb...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nakazono, Aoi, Adachi, Naoko, Takahashi, Hideyuki, Seki, Takahiro, Hamada, Daizo, Ueyama, Takehiko, Sakai, Norio, Saito, Naoaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153279/
https://ncbi.nlm.nih.gov/pubmed/30093405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002913
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