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Copper levels affect targeting of hypoxia-inducible factor 1α to the promoters of hypoxia-regulated genes
Hypoxia-inducible factor 1α (HIF-1α) is a transcription factor that regulates cellular responses to hypoxia. It controls the expression of both BCL2/adenovirus E1B 19-kDa protein–interacting protein 3 (BNIP3) and insulin-like growth factor 2 (IGF2). Previous studies have demonstrated that in hypoxia...
Gardado en:
| Publicado en: | J Biol Chem |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6153277/ https://ncbi.nlm.nih.gov/pubmed/30082314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001764 |
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