BCL-xL Is a Target Gene Regulated by Hypoxia-inducible Factor-1α

The transcription factor hypoxia-inducible factor-1α (HIF-1α) plays pivotal roles in physiology and pathophysiology. Constitutive or hypoxia-induced HIF-1α overexpression is observed in many types of cancers including prostate adenocarcinoma, in which it is associated with resistance to apoptosis an...

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Autors principals: Chen, Ni, Chen, Xueqin, Huang, Rui, Zeng, Hao, Gong, Jing, Meng, Wentong, Lu, Yiping, Zhao, Fang, Wang, Lin, Zhou, Qiao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Transcription, Chromatin, and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665055/
https://ncbi.nlm.nih.gov/pubmed/19211554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805997200
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