Mechanistic insights into the switch of αB-crystallin chaperone activity and self-multimerization

αB-Crystallin (αBc) is a small heat shock protein that protects cells against abnormal protein aggregation and disease-related degeneration. αBc is also a major structural protein that forms polydisperse multimers that maintain the liquid-like property of the eye lens. However, the relationship and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Liu, Zhenying, Wang, Chuchu, Li, Yichen, Zhao, Chunyu, Li, Tongzhou, Li, Dan, Zhang, Shengnan, Liu, Cong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153274/
https://ncbi.nlm.nih.gov/pubmed/30076220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004034
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