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Mechanistic insights into the switch of αB-crystallin chaperone activity and self-multimerization

αB-Crystallin (αBc) is a small heat shock protein that protects cells against abnormal protein aggregation and disease-related degeneration. αBc is also a major structural protein that forms polydisperse multimers that maintain the liquid-like property of the eye lens. However, the relationship and...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Liu, Zhenying, Wang, Chuchu, Li, Yichen, Zhao, Chunyu, Li, Tongzhou, Li, Dan, Zhang, Shengnan, Liu, Cong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153274/
https://ncbi.nlm.nih.gov/pubmed/30076220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004034
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