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Functionalized Cyclopentanes via Sc(III)-Catalyzed Intramolecular Enolate Alkylation

We report herein the intramolecular α-tert-alkylation of unsaturated β-ketoesters which gives rise to highly functionalized cyclopentanes. This strategy is characterized by its operational simplicity, mild reaction conditions and the use of scandium(III) triflate as a Lewis acid catalyst. Of interes...

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Foilsithe in:Tetrahedron
Main Authors: McAtee, Christopher C., Ellinwood, Duncan C., McAtee, Rory C., Schindler, Corinna S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152925/
https://ncbi.nlm.nih.gov/pubmed/30262933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2018.04.036
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