Probing the role of Proline -135 on the structure, stability, and cell proliferation activity of Human Acidic Fibroblast Growth Factor.

Human acidic fibroblast growth factor 1 (hFGF1) is a protein intricately involved in cell growth and tissue repair. In this study, we investigate the effect(s) of understanding the role of a conserved proline (P135), located in the heparin binding pocket, on the structure, stability, heparin binding...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Davis, Julie Eberle, Alghanmi, Arwa, Gundampati, Ravi Kumar, Jayanthi, Srinivas, Fields, Ellen, Armstrong, Monica, Weidling, Vanessa, Shah, Varun, Agrawal, Shilpi, Koppolu, Bhanu prasanth, Zaharoff, David A., Kumar, Thallapuranam Krishnaswamy Suresh
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152824/
https://ncbi.nlm.nih.gov/pubmed/30031837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.07.017
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