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Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
The cytoplasmic abundance of mRNAs is strictly controlled through a balance of production and degradation. Whereas the control of mRNA synthesis through transcription has been well characterized, less is known about the regulation of mRNA turnover, and a consensus model explaining the wide variation...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152797/ https://ncbi.nlm.nih.gov/pubmed/30192227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32536 |
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