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In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles

Idebenone (IDE) has been proposed for the treatment of neurodegenerative diseases involving mitochondria dysfunctions. Unfortunately, to date, IDE therapeutic treatments have not been as successful as expected. To improve IDE efficacy, in this work we describe a two-step approach: (1) synthesis of I...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Montenegro, Lucia, Modica, Maria N., Salerno, Loredana, Panico, Anna Maria, Crascì, Lucia, Puglisi, Giovanni, Romeo, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152785/
https://ncbi.nlm.nih.gov/pubmed/28555014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060887
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