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In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles

Idebenone (IDE) has been proposed for the treatment of neurodegenerative diseases involving mitochondria dysfunctions. Unfortunately, to date, IDE therapeutic treatments have not been as successful as expected. To improve IDE efficacy, in this work we describe a two-step approach: (1) synthesis of I...

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Опубликовано в: :Molecules
Главные авторы: Montenegro, Lucia, Modica, Maria N., Salerno, Loredana, Panico, Anna Maria, Crascì, Lucia, Puglisi, Giovanni, Romeo, Giuseppe
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152785/
https://ncbi.nlm.nih.gov/pubmed/28555014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060887
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