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In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles

Idebenone (IDE) has been proposed for the treatment of neurodegenerative diseases involving mitochondria dysfunctions. Unfortunately, to date, IDE therapeutic treatments have not been as successful as expected. To improve IDE efficacy, in this work we describe a two-step approach: (1) synthesis of I...

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書誌詳細
出版年:Molecules
主要な著者: Montenegro, Lucia, Modica, Maria N., Salerno, Loredana, Panico, Anna Maria, Crascì, Lucia, Puglisi, Giovanni, Romeo, Giuseppe
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152785/
https://ncbi.nlm.nih.gov/pubmed/28555014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060887
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