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In Vitro Antioxidant Activity of Idebenone Derivative-Loaded Solid Lipid Nanoparticles

Idebenone (IDE) has been proposed for the treatment of neurodegenerative diseases involving mitochondria dysfunctions. Unfortunately, to date, IDE therapeutic treatments have not been as successful as expected. To improve IDE efficacy, in this work we describe a two-step approach: (1) synthesis of I...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Montenegro, Lucia, Modica, Maria N., Salerno, Loredana, Panico, Anna Maria, Crascì, Lucia, Puglisi, Giovanni, Romeo, Giuseppe
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152785/
https://ncbi.nlm.nih.gov/pubmed/28555014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060887
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