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Synthesis and Bioactivity Characterization of Scutellarein Sulfonated Derivative

Scutellarin (1) has been widely used to treat acute cerebral infarction in clinic, but poor aqueous solubility decreases its bioavailability. Interestingly, scutellarin (1) could be metabolized into scutellarein (2) in vivo. In this study, a sulfonic group was introduced at position C-8 of scutellar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Gu, Ting, Zhong, Yue, Lu, Yu-Ting, Sun, Ying, Dong, Ze-Xi, Wu, Wen-Yu, Shi, Zhi-Hao, Li, Nian-Guang, Xue, Xin, Fang, Fang, Li, He-Min, Tang, Yu-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152701/
https://ncbi.nlm.nih.gov/pubmed/28635646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22061028
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