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An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin

Scutellarein (2), which is an important in vivo metabolite of scutellarin (1), was synthesized from 3,4,5-trimethoxyphenol (3) in high yield in four steps. This strategy relies on acetylation, aldolization, cyclization and hydrolysis reactions, respectively.

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dong, Ze-Xi, Li, Nian-Guang, Zhang, Peng-Xuan, Gu, Ting, Wu, Wen-Yu, Shi, Zhi-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272953/
https://ncbi.nlm.nih.gov/pubmed/26927039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21030263
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