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An Efficient Chemical Synthesis of Scutellarein: An in Vivo Metabolite of Scutellarin

Scutellarein (2), which is an important in vivo metabolite of scutellarin (1), was synthesized from 3,4,5-trimethoxyphenol (3) in high yield in four steps. This strategy relies on acetylation, aldolization, cyclization and hydrolysis reactions, respectively.

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Detalhes bibliográficos
Main Authors: Ze-Xi Dong, Nian-Guang Li, Peng-Xuan Zhang, Ting Gu, Wen-Yu Wu, Zhi-Hao Shi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-02-01
Colecção:Molecules
Assuntos:
Acesso em linha:http://www.mdpi.com/1420-3049/21/3/263
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