Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response

Drug repurposing is an effective approach to identify active drugs with known toxicity profiles for rare cancers such as ACC. The objective of this study was to determine the anticancer activity of combination treatment for ACC from previously identified candidate agents using quantitative high-thro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Nilubol, Naris, Boufraqech, Myriem, Zhang, Lisa, Gaskins, Kelli, Shen, Min, Zhang, Ya-Qin, Gara, Sudheer K., Austin, Christopher P., Kebebew, Electron
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2018
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152480/
https://ncbi.nlm.nih.gov/pubmed/30250647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26050
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