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Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response

Drug repurposing is an effective approach to identify active drugs with known toxicity profiles for rare cancers such as ACC. The objective of this study was to determine the anticancer activity of combination treatment for ACC from previously identified candidate agents using quantitative high-thro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nilubol, Naris, Boufraqech, Myriem, Zhang, Lisa, Gaskins, Kelli, Shen, Min, Zhang, Ya-Qin, Gara, Sudheer K., Austin, Christopher P., Kebebew, Electron
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152480/
https://ncbi.nlm.nih.gov/pubmed/30250647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26050
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