Synergistic combination of flavopiridol and carfilzomib targets commonly dysregulated pathways in adrenocortical carcinoma and has biomarkers of response

Drug repurposing is an effective approach to identify active drugs with known toxicity profiles for rare cancers such as ACC. The objective of this study was to determine the anticancer activity of combination treatment for ACC from previously identified candidate agents using quantitative high-thro...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Nilubol, Naris, Boufraqech, Myriem, Zhang, Lisa, Gaskins, Kelli, Shen, Min, Zhang, Ya-Qin, Gara, Sudheer K., Austin, Christopher P., Kebebew, Electron
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152480/
https://ncbi.nlm.nih.gov/pubmed/30250647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26050
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