COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation

Chronic obstructive pulmonary disease (COPD), an inflammatory disease of the lung, is an independent risk factor for lung cancer. Lung tissues obtained from human smokers with COPD and lung cancer demonstrate hypoxia and up-regulated hypoxia inducible factor-1 (HIF-1). HIF-1 activation is the centra...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: De la Garza, Maria Miguelina, Cumpian, Amber M., Daliri, Soudabeh, Castro-Pando, Susana, Umer, Misha, Gong, Lei, Khosravi, Nasim, Caetano, Mauricio S., Ramos-Castañeda, Marco, Flores, Alejandra Garza, Beltran, Evelyn C., Tran, Hai T., Tuvim, Michael J., Ostrin, Edwin J., Dickey, Burton F., Evans, Christopher M., Moghaddam, Seyed Javad
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2018
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152479/
https://ncbi.nlm.nih.gov/pubmed/30250643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26030
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