Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis

Tongue squamous cell carcinoma (TSCC) is a most aggressive head and neck cancer often associated with a poor survival rate. Yet, it always shows better prognosis in presence of HPV16 infection. NF-κB plays a pivotal role in carcinogenesis and chemo-radio resistance of cancer but its role in tongue c...

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Publicado en:Oncotarget
Autores principales: Gupta, Shilpi, Kumar, Prabhat, Kaur, Harsimrut, Sharma, Nishi, Gupta, Sunita, Saluja, Daman, Bharti, Alok C., Das, Bhudev
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152474/
https://ncbi.nlm.nih.gov/pubmed/30250646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26041
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