Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer

Tongue squamous cell carcinoma (TSCC) is most aggressive head and neck cancer often associated with HR-HPV infection. The role of AP-1 which is an essential regulator of HPV oncogene expression and tumorigenesis is not reported in tongue cancer. One hundred tongue tissue biopsies comprising precance...

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Pubblicato in:Sci Rep
Autori principali: Gupta, Shilpi, Kumar, Prabhat, Kaur, Harsimrut, Sharma, Nishi, Saluja, Daman, Bharti, Alok C., Das, Bhudev C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652185/
https://ncbi.nlm.nih.gov/pubmed/26581505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16811
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