A new drug combination significantly reduces kidney tumor progression in kidney mouse model

Tuberous sclerosis complex (TSC) disease is associated with tumors in many organs, particularly angiomyolipoma (AML) in the kidneys. Loss or inactivation of TSC1/2 results in high levels of HIF-α activity and VEGF expression. mTOR inhibitor (rapamycin) and the AMPK activator 5-aminoimidazole-4-carbo...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Liang, Sitai, Cuellar, Tiffanie, Nowacki, Maciej, Nayak, Bijaya K., Dong, Lily, Li, Boajie, Sharma, Kumar, Habib, Samy L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2018
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Priority Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152473/
https://ncbi.nlm.nih.gov/pubmed/30250638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26004
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