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Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA
mRNA based therapies hold great promise for the treatment of genetic diseases. However, this therapeutic approach suffers from multiple challenges including the short half-life of exogenously administered mRNA and subsequent protein production. Modulation of untranslated regions (UTR) represents one...
Shranjeno v:
| izdano v: | RNA Biol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152433/ https://ncbi.nlm.nih.gov/pubmed/29578372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1450054 |
| Oznake: |
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