The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats—A Comparison with Trimedoxime and the Oxime K203

The ability of two newly developed oximes (K305, K307) to protect tabun-poisoned rats from tabun-induced inhibition of brain acetylcholinesterase, acute neurotoxic signs and symptoms and brain damage was compared with that of the oxime K203 and trimedoxime. The reactivating and neuroprotective effec...

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Veröffentlicht in:Molecules
Hauptverfasser: Kassa, Jiri, Misik, Jan, Hatlapatkova, Jana, Zdarova Karasova, Jana, Sepsova, Vendula, Caisberger, Filip, Pejchal, Jaroslav
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152392/
https://ncbi.nlm.nih.gov/pubmed/28696367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071152
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