Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors

In this work, we reported the application and validation of an improved high-performance liquid chromatography method coupled with a fluorimetric detector (HPLC-FL) to screen the activity of two heterocyclic derivatives reported as serine palmitoyl transferase (SPT) inhibitors. The analytical condit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Bertini, Simone, Saccomanni, Giuseppe, Del Carlo, Sara, Digiacomo, Maria, Gargini, Claudia, Piano, Ilaria, Campisi, Giuseppe Matteo, Ghidoni, Riccardo, Macchia, Marco, Manera, Clementina
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152383/
https://ncbi.nlm.nih.gov/pubmed/28714922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071198
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