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Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents

In this study two series of fluconazole derivatives bearing nitrotriazole (series A) or piperazine ethanol (series B) side chain were designed and synthesized and then docked in the active site of lanosterol 14α-demethylase enzyme (1EA1) using the Autodock 4.2 program (The scripps research institute...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Sadeghpour, Hossein, Khabnadideh, Soghra, Zomorodian, Kamiar, Pakshir, Keyvan, Hoseinpour, Khadijeh, Javid, Nabiollah, Faghih-Mirzaei, Ehsan, Rezaei, Zahra
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152269/
https://ncbi.nlm.nih.gov/pubmed/28698522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071150
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