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Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents

In this study two series of fluconazole derivatives bearing nitrotriazole (series A) or piperazine ethanol (series B) side chain were designed and synthesized and then docked in the active site of lanosterol 14α-demethylase enzyme (1EA1) using the Autodock 4.2 program (The scripps research institute...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Sadeghpour, Hossein, Khabnadideh, Soghra, Zomorodian, Kamiar, Pakshir, Keyvan, Hoseinpour, Khadijeh, Javid, Nabiollah, Faghih-Mirzaei, Ehsan, Rezaei, Zahra
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152269/
https://ncbi.nlm.nih.gov/pubmed/28698522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071150
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