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Design, Synthesis, and Biological Activity of New Triazole and Nitro-Triazole Derivatives as Antifungal Agents

In this study two series of fluconazole derivatives bearing nitrotriazole (series A) or piperazine ethanol (series B) side chain were designed and synthesized and then docked in the active site of lanosterol 14α-demethylase enzyme (1EA1) using the Autodock 4.2 program (The scripps research institute...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Sadeghpour, Hossein, Khabnadideh, Soghra, Zomorodian, Kamiar, Pakshir, Keyvan, Hoseinpour, Khadijeh, Javid, Nabiollah, Faghih-Mirzaei, Ehsan, Rezaei, Zahra
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152269/
https://ncbi.nlm.nih.gov/pubmed/28698522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071150
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