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Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date

The cytochrome P450 (CYP) family 1A enzymes, CYP1A1 and CYP1A2, are two of the most important enzymes implicated in the metabolism of endogenous and exogenous compounds through oxidation. These enzymes are also known to metabolize environmental procarcinogens into carcinogenic species, leading to th...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Sridhar, Jayalakshmi, Goyal, Navneet, Liu, Jiawang, Foroozesh, Maryam
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152251/
https://ncbi.nlm.nih.gov/pubmed/28698457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071143
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