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Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents

In this study we designed and synthesized a series of new hesperetin derivatives on the basis of the structural characteristics of acetylcholinesterase (AChE) dual-site inhibitors. The activity of the novel derivatives was also evaluated. Results showed that the synthesized hesperetin derivatives di...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Li, Bo, Huang, Ai-Ling, Zhang, Yi-Long, Li, Zeng, Ding, Hai-Wen, Huang, Cheng, Meng, Xiao-Ming, Li, Jun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152180/
https://ncbi.nlm.nih.gov/pubmed/28672874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22071067
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