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Enzymatic Synthesis of N-Acetyllactosamine (LacNAc) Type 1 Oligomers and Characterization as Multivalent Galectin Ligands

Repeats of the disaccharide unit N-acetyllactosamine (LacNAc) occur as type 1 (Galβ1, 3GlcNAc) and type 2 (Galβ1, 4GlcNAc) glycosylation motifs on glycoproteins and glycolipids. The LacNAc motif acts as binding ligand for lectins and is involved in many biological recognition events. To the best of...

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Publicat a:Molecules
Autors principals: Fischöder, Thomas, Laaf, Dominic, Dey, Carina, Elling, Lothar
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152129/
https://ncbi.nlm.nih.gov/pubmed/28796164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081320
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