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Biotinylated N-Acetyllactosamine- and N,N-Diacetyllactosamine-Based Oligosaccharides as Novel Ligands for Human Galectin-3 †

Galectin inhibitor design is an emerging research field due to the involvement of galectins in cancer. Galectin-3, in particular, plays an important role in tumor progression. To generate inhibitors, modifications of the glycan structure can be introduced. Conjugation of hydrophobic compounds to sac...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Böcker, Sophia, Elling, Lothar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590477/
https://ncbi.nlm.nih.gov/pubmed/28952509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering4020031
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