Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents

A medium-throughput screen using Mycobacterium tuberculosis H37Rv was employed to screen an in-house library of structurally diverse compounds for antimycobacterial activity. In this initial screen, eleven 7-substituted coumarin derivatives with confirmed monoamine oxidase-B and cholinesterase inhib...

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Publicado en:Molecules
Main Authors: Kapp, Erika, Visser, Hanri, Sampson, Samantha L., Malan, Sarel F., Streicher, Elizabeth M., Foka, Germaine B., Warner, Digby F., Omoruyi, Sylvester I., Enogieru, Adaze B., Ekpo, Okobi E., Zindo, Frank T., Joubert, Jacques
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151660/
https://ncbi.nlm.nih.gov/pubmed/28973990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101644
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