Production of Single-Chain Fv Antibodies Specific for GA-Pyridine, an Advanced Glycation End-Product (AGE), with Reduced Inter-Domain Motion

Due to their lower production cost compared with monoclonal antibodies, single-chain variable fragments (scFvs) have potential for use in several applications, such as for diagnosis and treatment of a range of diseases, and as sensor elements. However, the usefulness of scFvs is limited by inhomogen...

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Publicado no:Molecules
Main Authors: Fukuda, Natsuki, Noi, Kentaro, Weng, Lidong, Kobashigawa, Yoshihiro, Miyazaki, Hiromi, Wakeyama, Yukari, Takaki, Michiyo, Nakahara, Yusuke, Tatsuno, Yuka, Uchida-Kamekura, Makiyo, Suwa, Yoshiaki, Sato, Takashi, Ichikawa-Tomikawa, Naoki, Nomizu, Motoyoshi, Fujiwara, Yukio, Ohsaka, Fumina, Saito, Takashi, Maenaka, Katsumi, Kumeta, Hiroyuki, Shinya, Shoko, Kojima, Chojiro, Ogura, Teru, Morioka, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151396/
https://ncbi.nlm.nih.gov/pubmed/28994732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101695
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