A Novel Strategy for Inducing the Antitumor Effects of Triterpenoid Compounds: Blocking the Protumoral Functions of Tumor-Associated Macrophages via STAT3 Inhibition

Por Fujiwara, Yukio, Takeya, Motohiro, Komohara, Yoshihiro
Publicado em 2014

Citric acid inhibits development of cataracts, proteinuria and ketosis in streptozotocin (type1) diabetic rats

Por Nagai, Ryoji, Nagai, Mime, Shimasaki, Satoko, Baynes, John W., Fujiwara, Yukio
Publicado em 2010

Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling

Por FUJIWARA, YUKIO, TAKAISHI, KIYOMI, NAKAO, JUNKO, IKEDA, TSUYOSHI, KATABUCHI, HIDETAKA, TAKEYA, MOTOHIRO, KOMOHARA, YOSHIHIRO
Publicado em 2013

Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity

Por Sakashita, Naomi, Chang, Catherine C. Y., Lei, Xiaofeng, Fujiwara, Yukio, Takeya, Motohiro, Chang, Ta-Yuan
Publicado em 2010

ACAT1-associated Late Endosomes/Lysosomes Significantly Improve Impaired Intracellular Cholesterol Metabolism and the Survival of Niemann-Pick Type C Mice

Por Kamikawa, Masashi, Lei, XiaoFeng, Fujiwara, Yukio, Nishitsuji, Kazuchika, Mizuta, Hiroshi, Takeya, Motohiro, Sakashita, Naomi
Publicado em 2014

Detection of AGEs as markers for carbohydrate metabolism and protein denaturation

Por Nagai, Ryoji, Shirakawa, Jun-ichi, Fujiwara, Yukio, Ohno, Rei-ichi, Moroishi, Narumi, Sakata, Noriyuki, Nagai, Mime
Publicado em 2014

Guanylate-binding protein 5 is a marker of interferon-γ-induced classically activated macrophages

Por Fujiwara, Yukio, Hizukuri, Yoshiyuki, Yamashiro, Kyoko, Makita, Naoyuki, Ohnishi, Koji, Takeya, Motohiro, Komohara, Yoshihiro, Hayashi, Yasuhiro
Publicado no Clin Transl Immunology (2016)

TIM-3 expression in lymphoma cells predicts chemoresistance in patients with adult T-cell leukemia/lymphoma

Por Horlad, Hasita, Ohnishi, Koji, Ma, Chaoya, Fujiwara, Yukio, Niino, Daisuke, Ohshima, Koichi, Jinushi, Masahisa, Matsuoka, Masao, Takeya, Motohiro, Komohara, Yoshihiro
Publicado no Oncol Lett (2016)

Dysregulation of dimethylargininedimethylaminohydrolase/asymmetric dimethylarginine pathway in rat type II diabetic nephropathy

Por Lai, Ying-Ling, Aoyama, Sae, Ohata, Miyuki, Otsuka, Nami, Shiokawa, Hidemi, Tomono, Susumu, Fujiwara, Yukio, Kanazawa, Hiroaki, Miyoshi, Noriyuki, Ohshima, Hiroshi
Publicado em 2012

An IL‐27/Stat3 axis induces expression of programmed cell death 1 ligands (PD‐L1/2) on infiltrating macrophages in lymphoma

Por Horlad, Hasita, Ma, Chaoya, Yano, Hiromu, Pan, Cheng, Ohnishi, Koji, Fujiwara, Yukio, Endo, Shinya, Kikukawa, Yoshitaka, Okuno, Yutaka, Matsuoka, Masao, Takeya, Motohiro, Komohara, Yoshihiro
Publicado no Cancer Sci (2016)

Pleiotropic Effects of Levofloxacin, Fluoroquinolone Antibiotics, against Influenza Virus-Induced Lung Injury

Por Enoki, Yuki, Ishima, Yu, Tanaka, Ryota, Sato, Keizo, Kimachi, Kazuhiko, Shirai, Tatsuya, Watanabe, Hiroshi, Chuang, Victor T. G., Fujiwara, Yukio, Takeya, Motohiro, Otagiri, Masaki, Maruyama, Toru
Publicado no PLoS One (2015)

Non-invasive measurement of skin autofluorescence to evaluate diabetic complications

Por Yamanaka, Mikihiro, Matsumura, Takeshi, Ohno, Rei-ichi, Fujiwara, Yukio, Shinagawa, Masatoshi, Sugawa, Hikari, Hatano, Kota, Shirakawa, Jun-ichi, Kinoshita, Hiroyuki, Ito, Kenji, Sakata, Noriyuki, Araki, Eiichi, Nagai, Ryoji
Publicado no J Clin Biochem Nutr (2016)

Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages

Por Tsuboki, Junko, Fujiwara, Yukio, Horlad, Hasita, Shiraishi, Daisuke, Nohara, Toshihiro, Tayama, Shingo, Motohara, Takeshi, Saito, Yoichi, Ikeda, Tsuyoshi, Takaishi, Kiyomi, Tashiro, Hironori, Yonemoto, Yukihiro, Katabuchi, Hidetaka, Takeya, Motohiro, Komohara, Yoshihiro
Publicado no Sci Rep (2016)

Infiltration of tumor‐associated macrophages is involved in CD44 expression in clear cell renal cell carcinoma

Por Ma, Chaoya, Komohara, Yoshihiro, Ohnishi, Koji, Shimoji, Tetsu, Kuwahara, Nao, Sakumura, Yasuo, Matsuishi, Kozue, Fujiwara, Yukio, Motoshima, Takanobu, Takahashi, Wataru, Yamada, Sohsuke, Kitada, Shohei, Fujimoto, Naohiro, Nakayama, Toshiyuki, Eto, Masatoshi, Takeya, Motohiro
Publicado no Cancer Sci (2016)

Promotion of atherosclerosis by Helicobacter cinaedi infection that involves macrophage-driven proinflammatory responses

Por Khan, Shahzada, Rahman, H. N. Ashiqur, Okamoto, Tatsuya, Matsunaga, Tetsuro, Fujiwara, Yukio, Sawa, Tomohiro, Yoshitake, Jun, Ono, Katsuhiko, Ahmed, Khandaker Ahtesham, Rahaman, Md Mizanur, Oyama, Kohta, Takeya, Motohiro, Ida, Tomoaki, Kawamura, Yoshiaki, Fujii, Shigemoto, Akaike, Takaaki
Publicado em 2014