Effects of Treatment Delay on Efficacy of Tecovirimat Following Lethal Aerosol Monkeypox Virus Challenge in Cynomolgus Macaques

BACKGROUND: Tecovirimat (ST-246) is being developed as an antiviral therapeutic for smallpox for use in the event of an accidental or intentional release. The last reported case of smallpox was 1978 but the potential for use of variola virus for biowarfare has renewed interest in smallpox antiviral...

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Bibliografiske detaljer
Udgivet i:J Infect Dis
Main Authors: Russo, Andrew T, Grosenbach, Douglas W, Brasel, Trevor L, Baker, Robert O, Cawthon, Andrew G, Reynolds, Erin, Bailey, Tara, Kuehl, Philip J, Sugita, Victoria, Agans, Krystle, Hruby, Dennis E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151088/
https://ncbi.nlm.nih.gov/pubmed/29982575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy326
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