Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus challenge()()

Naturally occurring smallpox has been eradicated but research stocks of variola virus (VARV), the causative agent of smallpox, still exist in secure laboratories. Clandestine stores of the virus or resurrection of VARV via synthetic biology are possible and have led to concerns that VARV could be us...

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Udgivet i:Vaccine
Main Authors: Russo, Andrew T., Berhanu, Aklile, Bigger, Catherine B., Prigge, Jon, Silvera, Peter M., Grosenbach, Douglas W., Hruby, Dennis
Format: Artigo
Sprog:Inglês
Udgivet: The Authors. Published by Elsevier Ltd. 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954297/
https://ncbi.nlm.nih.gov/pubmed/31677948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.10.049
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