Assessment of the Protective Effect of Imvamune and Acam2000 Vaccines against Aerosolized Monkeypox Virus in Cynomolgus Macaques

To support the licensure of a new and safer vaccine to protect people against smallpox, a monkeypox model of infection in cynomolgus macaques, which simulates smallpox in humans, was used to evaluate two vaccines, Acam2000 and Imvamune, for protection against disease. Animals vaccinated with a singl...

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Detalhes bibliográficos
Main Authors: Hatch, Graham J., Graham, Victoria A., Bewley, Kevin R., Tree, Julia A., Dennis, Mike, Taylor, Irene, Funnell, Simon G. P., Bate, Simon R., Steeds, Kimberley, Tipton, Thomas, Bean, Thomas, Hudson, Laura, Atkinson, Deborah J., McLuckie, Gemma, Charlwood, Melanie, Roberts, Allen D. G., Vipond, Julia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700201/
https://ncbi.nlm.nih.gov/pubmed/23658452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03481-12
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