Sequence of Pathogenic Events in Cynomolgus Macaques Infected with Aerosolized Monkeypox Virus

To evaluate new vaccines when human efficacy studies are not possible, the FDA's “Animal Rule” requires well-characterized models of infection. Thus, in the present study, the early pathogenic events of monkeypox infection in nonhuman primates, a surrogate for variola virus infection, were char...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tree, J. A., Hall, G., Pearson, G., Rayner, E., Graham, V. A., Steeds, K., Bewley, K. R., Hatch, G. J., Dennis, M., Taylor, I., Roberts, A. D., Funnell, S. G. P., Vipond, J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442344/
https://ncbi.nlm.nih.gov/pubmed/25653439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03029-14
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