Repeated high-dose (5 × 10(8) TCID(50)) toxicity study of a third generation smallpox vaccine (IMVAMUNE) in New Zealand white rabbits

Concern over the release of variola virus as an agent of bioterrorism remains high and a rapid vaccination regimen is desirable for use in the event of a confirmed release of virus. A single, high-dose (5×10(8) TCID(50)) of Bavarian Nordic's IMVAMUNE was tested in a Phase-II clinical trial, in...

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Dades bibliogràfiques
Publicat a:Hum Vaccin Immunother
Autors principals: Tree, Julia A., Hall, Graham, Rees, Peter, Vipond, Julia, Funnell, Simon G. P., Roberts, Allen D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964806/
https://ncbi.nlm.nih.gov/pubmed/26836234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1134070
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