Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection

We examined associations of 5 plasma choline metabolites with carotid plaque among 520 HIV-infected and 217 HIV-uninfected participants (112 incident plaque cases) over 7 years. After multivariable adjustment, higher gut microbiota-related metabolite trimethylamine-N-oxide (TMAO) was associated with...

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Publicado en:J Infect Dis
Autores principales: Shan, Zhilei, Clish, Clary B, Hua, Simin, Scott, Justin M, Hanna, David B, Burk, Robert D, Haberlen, Sabina A, Shah, Sanjiv J, Margolick, Joseph B, Sears, Cynthia L, Post, Wendy S, Landay, Alan L, Lazar, Jason M, Hodis, Howard N, Anastos, Kathryn, Kaplan, Robert C, Qi, Qibin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151074/
https://ncbi.nlm.nih.gov/pubmed/29912352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy356
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