Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection

We examined associations of 5 plasma choline metabolites with carotid plaque among 520 HIV-infected and 217 HIV-uninfected participants (112 incident plaque cases) over 7 years. After multivariable adjustment, higher gut microbiota-related metabolite trimethylamine-N-oxide (TMAO) was associated with...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Shan, Zhilei, Clish, Clary B, Hua, Simin, Scott, Justin M, Hanna, David B, Burk, Robert D, Haberlen, Sabina A, Shah, Sanjiv J, Margolick, Joseph B, Sears, Cynthia L, Post, Wendy S, Landay, Alan L, Lazar, Jason M, Hodis, Howard N, Anastos, Kathryn, Kaplan, Robert C, Qi, Qibin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151074/
https://ncbi.nlm.nih.gov/pubmed/29912352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy356
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