Plasma Tryptophan-Kynurenine Metabolites Are Altered in Human Immunodeficiency Virus Infection and Associated With Progression of Carotid Artery Atherosclerosis

BACKGROUND: It is unknown whether disrupted tryptophan catabolism is associated with cardiovascular disease (CVD) in human immunodeficiency virus (HIV)–infected individuals. METHODS: Plasma tryptophan and kynurenic acid were measured in 737 women and men (520 HIV+, 217 HIV−) from the Women’s Interag...

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Veröffentlicht in:Clin Infect Dis
Hauptverfasser: Qi, Qibin, Hua, Simin, Clish, Clary B, Scott, Justin M, Hanna, David B, Wang, Tao, Haberlen, Sabina A, Shah, Sanjiv J, Glesby, Marshall J, Lazar, Jason M, Burk, Robert D, Hodis, Howard N, Landay, Alan L, Post, Wendy S, Anastos, Kathryn, Kaplan, Robert C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031054/
https://ncbi.nlm.nih.gov/pubmed/29415228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy053
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