TEM8 functions as a receptor for uPA and mediates uPA-stimulated EGFR phosphorylation

BACKGROUND: TEM8 is a cell membrane protein predominantly expressed in tumor endothelium, which serves as a receptor for the protective antigen (PA) of anthrax toxin. However, the physiological ligands for TEM8 remain unknown. RESULTS: Here we identified uPA as an interacting partner of TEM8. Bindin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Commun Signal
Egile Nagusiak: Zhang, Lian-Cheng, Shao, Yong, Gao, Li-Hua, Liu, Jin, Xi, Yong-Yi, Xu, Yin, Wu, Chutse, Chen, Wei, Chen, Hui-Peng, Wang, You-Liang, Duan, Hai-Feng, Hu, Xian-Wen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151050/
https://ncbi.nlm.nih.gov/pubmed/30241478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0272-8
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak