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Modulation of Cellular Migration and Survival by c-Myc through the Downregulation of Urokinase (uPA) and uPA Receptor

It has been proposed that c-Myc proapoptotic activity accounts for most of its restraint of tumor formation. We established a telomerase-immortalized human epithelial cell line expressing an activatable c-Myc protein. We found that c-Myc activation induces, in addition to increased sensitivity to ap...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alfano, Daniela, Votta, Giuseppina, Schulze, Almut, Downward, Julian, Caputi, Mario, Stoppelli, Maria Patrizia, Iaccarino, Ingram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838082/
https://ncbi.nlm.nih.gov/pubmed/20123981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01442-09
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