Genome-wide association study of response to tumour necrosis factor inhibitor therapy in rheumatoid arthritis

Rheumatoid arthritis (RA) is characterised by chronic synovial joint inflammation. Treatment has been revolutionised by tumour necrosis factor alpha inhibitors (TNFi) but each available drug shows a significant non-response rate. We conducted a genome-wide association study of 1752 UK RA TNFi-treate...

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Bibliographic Details
Published in:Pharmacogenomics J
Main Authors: Massey, Jonathan, Plant, Darren, Hyrich, Kimme, Morgan, Ann W., Wilson, Anthony G., Spiliopoulou, Athina, Colombo, Marco, McKeigue, Paul, Isaacs, John, Cordell, Heather, Pitzalis, Costantino, Barton, Anne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150911/
https://ncbi.nlm.nih.gov/pubmed/30166627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41397-018-0040-6
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