Genome-Wide Association Study of Genetic Predictors of Anti–Tumor Necrosis Factor Treatment Efficacy in Rheumatoid Arthritis Identifies Associations with Polymorphisms at Seven Loci

OBJECTIVE: Anti–tumor necrosis factor (anti-TNF) agents are successful therapies in rheumatoid arthritis (RA); however, inadequate response occurs in 30–40% of patients treated. Knowledge of the genetic factors that influence response may facilitate personalized therapy. The purpose of this study wa...

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Detalhes bibliográficos
Main Authors: Plant, Darren, Bowes, John, Potter, Catherine, Hyrich, Kimme L, Morgan, Ann W, Wilson, Anthony G, Isaacs, John D, Barton, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084508/
https://ncbi.nlm.nih.gov/pubmed/21061259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30130
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