Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment

BACKGROUND: Despite the success of TNF-inhibitor therapy in rheumatoid arthritis treatment, up to 40% of patients fail to respond adequately. This study aimed to identify transcriptome-based biomarkers of adalimumab response in rheumatoid arthritis (RA) to aid timely switching in non-responder patie...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: OIiver, James, Nair, Nisha, Orozco, Gisela, Smith, Samantha, Hyrich, Kimme L., Morgan, Ann, Isaacs, John, Wilson, Anthony G., Barton, Anne, Plant, Darren
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948368/
https://ncbi.nlm.nih.gov/pubmed/33691749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02451-9
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