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DNA Methylation and FoxO3a Regulate PHLPP1 Expression in Chondrocytes
The protein phosphatase Phlpp1 is an essential enzyme for proper chondrocyte function. Altered Phlpp1 levels are associated with cancer and degenerative diseases such as osteoarthritis. While much is known about the post-transcriptional mechanisms controlling Phlpp1 levels, transcriptional regulatio...
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| Publicado no: | J Cell Biochem |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150803/ https://ncbi.nlm.nih.gov/pubmed/29775231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27056 |
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