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Enhanced Specific Activity by Multichelation of Exendin-3 Leads To Improved Image Quality and In Vivo Beta Cell Imaging
[Image: see text] Glucagon-like peptide-1 receptor (GLP-1R) targeting using radiolabeled exendin is a promising approach to noninvasively visualize and determine beta cell mass (BCM), which could help to unravel the pathophysiology of diabetes. However, saturation of the GLP-1R on beta cells occurs...
Shranjeno v:
| izdano v: | Mol Pharm |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2017
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150723/ https://ncbi.nlm.nih.gov/pubmed/29226686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00853 |
| Oznake: |
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