Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin

PURPOSE: Noninvasive beta cell mass (BCM) quantification is a crucial tool to understand diabetes development and progression. [(111)In]exendin is a promising agent for in vivo beta cell imaging, but tracer testing has been hampered by the lack of well-defined rodent models. PROCEDURES: Biodistribut...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Willekens, Stefanie M. A., Joosten, Lieke, Boerman, Otto C., Balhuizen, Alexander, Eizirik, Decio L., Gotthardt, Martin, Brom, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010585/
https://ncbi.nlm.nih.gov/pubmed/26886298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0936-y
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